Cellular membranes
نویسندگان
چکیده
منابع مشابه
Computational 'microscopy' of cellular membranes.
Computational 'microscopy' refers to the use of computational resources to simulate the dynamics of a molecular system. Tuned to cell membranes, this computational 'microscopy' technique is able to capture the interplay between lipids and proteins at a spatio-temporal resolution that is unmatched by other methods. Recent advances allow us to zoom out from individual atoms and molecules to supra...
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Force-regulation at cellular membranes relies on dynamic molecular platforms that integrate intra- and extracellular signals to control cell shape and function. To correctly respond to a continuously changing environment, activity of these platforms needs to be tightly controlled in space and time. Over the last few years, curvature-dependent mechano-chemical signal translation—a receptor-indep...
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Phosphatidylserine, a phospholipid with a negatively charged head-group, is an important constituent of eukaryotic cellular membranes. On the plasma membrane, rather than being evenly distributed, phosphatidylserine is found preferentially in the inner leaflet. Disruption of this asymmetry, leading to the appearance of phosphatidylserine on the surface of the cell, is known to play a central ro...
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shackles imposed by the conventional wisdom that ‘the proper study of mankind is man’. They were less successful in convincing this reviewer that any of the model systems discussed in the book were currently pertinent to the practising clinical psychiatrist. Nevertheless, the book justifies the claim that model systems in this difficult field have a future, and much of the work is scientificall...
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Much has been learned about the role of exofacial phosphatidylserine (PS) in apoptosis and blood clotting using annexin V. However, because annexins are impermeant and unable to bind PS at low calcium concentration, they are unsuitable for intracellular use. Thus little is known about the topology and dynamics of PS in the endomembranes of normal cells. We used two new probes-green fluorescent ...
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ژورنال
عنوان ژورنال: Science
سال: 1992
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.1439794